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9CWZ

Crystal structure of HLA-A*03:02 in complex with a mutant PIK3CA peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HLA class I histocompatibility antigen A alpha chainpolymer27431613.81UniProt (C5IWY0)Homo sapiens (human)MHC class I antigen
2B
(B)
Beta-2-microglobulinpolymer10011879.41UniProt (P61769)Homo sapiens (human)
3C
(C)
Mutant PIK3CA peptidepolymer9972.11UniProt (P42336)Homo sapiens
4D, E, F, G, H...
(A, B)
GLYCEROLnon-polymer92.110Chemie (GOL)
5N, O, P
(A, B, C)
waterwater18.0331Chemie (HOH)
Sequence modifications
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-initiating methionine
C: 1 - 9 (UniProt: P42336)
PDBExternal DatabaseDetails
Leu 2His 1047engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight44465.3
Non-Polymers*Number of molecules10
Total formula weight920.9
All*Total formula weight45386.2
*Water molecules are not included.

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PDB entries from 2026-02-11

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