9CWO

Cryo EM structure of Nipah virus L-P polymerase complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase L	polymer	1619	185001.1	1	UniProt (Q4VCP4) UniProt (by SIFTS) (Q997F0)	Henipavirus nipahense	Protein L,Large structural protein,Replicase,Transcriptase
2	B, C, D, E (F, C, G, E)	Phosphoprotein	polymer	717	79183.2	4	UniProt (Q4VCQ1)	Henipavirus nipahense

Sequence modifications

A: 2 - 1463 (UniProt: Q4VCP4)

PDB	External Database	Details
Met -155	-	initiating methionine
Ala -154	-	expression tag
Ser -153	-	expression tag
His -152	-	expression tag
His -151	-	expression tag
His -150	-	expression tag
His -149	-	expression tag
His -148	-	expression tag
His -147	-	expression tag
His -146	-	expression tag
His -145	-	expression tag
His -144	-	expression tag
His -143	-	expression tag
Ala -142	-	expression tag
Gln -141	-	expression tag
His -140	-	expression tag
Asp -139	-	expression tag
Glu -138	-	expression tag
Ala -137	-	expression tag
Val -136	-	expression tag
Asp -135	-	expression tag
Asn -134	-	expression tag
Lys -133	-	expression tag
Phe -132	-	expression tag
Asn -131	-	expression tag
Lys -130	-	expression tag
Glu -129	-	expression tag
Gln -128	-	expression tag
Gln -127	-	expression tag
Asn -126	-	expression tag
Ala -125	-	expression tag
Phe -124	-	expression tag
Tyr -123	-	expression tag
Glu -122	-	expression tag
Ile -121	-	expression tag
Leu -120	-	expression tag
His -119	-	expression tag
Leu -118	-	expression tag
Pro -117	-	expression tag
Asn -116	-	expression tag
Leu -115	-	expression tag
Asn -114	-	expression tag
Glu -113	-	expression tag
Glu -112	-	expression tag
Gln -111	-	expression tag
Arg -110	-	expression tag
Asn -109	-	expression tag
Ala -108	-	expression tag
Phe -107	-	expression tag
Ile -106	-	expression tag
Gln -105	-	expression tag
Ser -104	-	expression tag
Leu -103	-	expression tag
Lys -102	-	expression tag
Asp -101	-	expression tag
Asp -100	-	expression tag
Pro -99	-	expression tag
Ser -98	-	expression tag
Gln -97	-	expression tag
Ser -96	-	expression tag
Ala -95	-	expression tag
Asn -94	-	expression tag
Arg -93	-	expression tag
Arg -92	-	expression tag
Ala -91	-	expression tag
Glu -90	-	expression tag
Ala -89	-	expression tag
Lys -88	-	expression tag
Lys -87	-	expression tag
Leu -86	-	expression tag
Asn -85	-	expression tag
Asp -84	-	expression tag
Ala -83	-	expression tag
Gln -82	-	expression tag
Ala -81	-	expression tag
Pro -80	-	expression tag
Lys -79	-	expression tag
Val -78	-	expression tag
Asp -77	-	expression tag
Asn -76	-	expression tag
Lys -75	-	expression tag
Phe -74	-	expression tag
Asn -73	-	expression tag
Lys -72	-	expression tag
Glu -71	-	expression tag
Gln -70	-	expression tag
Gln -69	-	expression tag
Asn -68	-	expression tag
Ala -67	-	expression tag
Phe -66	-	expression tag
Tyr -65	-	expression tag
Glu -64	-	expression tag
Ile -63	-	expression tag
Leu -62	-	expression tag
His -61	-	expression tag
Leu -60	-	expression tag
Pro -59	-	expression tag
Asn -58	-	expression tag
Leu -57	-	expression tag
Asn -56	-	expression tag
Glu -55	-	expression tag
Glu -54	-	expression tag
Gln -53	-	expression tag
Arg -52	-	expression tag
Asn -51	-	expression tag
Ala -50	-	expression tag
Phe -49	-	expression tag
Ile -48	-	expression tag
Gln -47	-	expression tag
Ser -46	-	expression tag
Leu -45	-	expression tag
Lys -44	-	expression tag
Asp -43	-	expression tag
Asp -42	-	expression tag
Pro -41	-	expression tag
Ser -40	-	expression tag
Gln -39	-	expression tag
Ser -38	-	expression tag
Ala -37	-	expression tag
Asn -36	-	expression tag
Leu -35	-	expression tag
Leu -34	-	expression tag
Ala -33	-	expression tag
Glu -32	-	expression tag
Ala -31	-	expression tag
Lys -30	-	expression tag
Lys -29	-	expression tag
Leu -28	-	expression tag
Asn -27	-	expression tag
Asp -26	-	expression tag
Ala -25	-	expression tag
Gln -24	-	expression tag
Ala -23	-	expression tag
Pro -22	-	expression tag
Lys -21	-	expression tag
Val -20	-	expression tag
Asp -19	-	expression tag
Ala -18	-	expression tag
Asn -17	-	expression tag
Gly -16	-	expression tag
Gly -15	-	expression tag
Gly -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Gly -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
Leu -6	-	expression tag
Glu -5	-	expression tag
Val -4	-	expression tag
Leu -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Pro 1	-	expression tag

F, C, G, E: 1 - 709 (UniProt: Q4VCQ1)

PDB	External Database	Details
Trp 710	-	expression tag
Ser 711	-	expression tag
His 712	-	expression tag
Pro 713	-	expression tag
Gln 714	-	expression tag
Phe 715	-	expression tag
Glu 716	-	expression tag
Lys 717	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	501734.1
All*	Total formula weight	501734.1

*Water molecules are not included.