9CUX
Crystal Structure of SETDB1 Tudor domain in complex with UNC100016
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Histone-lysine N-methyltransferase SETDB1 | polymer | 225 | 26337.3 | 1 | UniProt (Q15047) Pfam (PF18300) Pfam (PF18359) Pfam (PF18358) | Homo sapiens (human) | ERG-associated protein with SET domain,ESET,Histone H3-K9 methyltransferase 4,H3-K9-HMTase 4,Lysine N-methyltransferase 1E,SET domain bifurcated 1 |
2 | B (A) | (2E)-N-(4-{[6-(dimethylamino)hexyl]amino}-2-{[5-(dimethylamino)pentyl]amino}quinazolin-6-yl)but-2-enamide | non-polymer | 483.7 | 1 | Chemie (A1AZ5) | |||
3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | E, F, G, H, I... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
5 | N, O, P, Q (A) | UNKNOWN ATOM OR ION | non-polymer | 4 | Chemie (UNX) | ||||
6 | R (A) | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A: 196 - 403 (UniProt: Q15047)
PDB | External Database | Details |
---|---|---|
Met 179 | - | initiating methionine |
His 180 | - | expression tag |
His 181 | - | expression tag |
His 182 | - | expression tag |
His 183 | - | expression tag |
His 184 | - | expression tag |
His 185 | - | expression tag |
Ser 186 | - | expression tag |
Ser 187 | - | expression tag |
Gly 188 | - | expression tag |
Arg 189 | - | expression tag |
Glu 190 | - | expression tag |
Asn 191 | - | expression tag |
Leu 192 | - | expression tag |
Tyr 193 | - | expression tag |
Phe 194 | - | expression tag |
Gln 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26337.3 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1234.4 | |
All* | Total formula weight | 27571.8 |