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9CUO

Crystal structure of CRBN with compound 3

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Protein cereblonpolymer11312541.46UniProt (Q96SW2)
Pfam (PF03226)
In PDB
Homo sapiens (human)
2E, A, B, F, C...ZINC IONnon-polymer65.46Chemie (ZN)
3E, A, B, F, C...(3S)-3-(3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidine-2,6-dionenon-polymer259.36Chemie (A1A0J)
4E, A, B, F, C...SULFATE IONnon-polymer96.113Chemie (SO4)
5D, E, A, B, F1,2-ETHANEDIOLnon-polymer62.112Chemie (EDO)
6waterwater18.0305Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 319 - 427 (UniProt: Q96SW2)
PDBExternal DatabaseDetails
Ser 315-expression tag
Gly 316-expression tag
Ser 317-expression tag
Pro 318-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight75248.7
Non-Polymers*Number of molecules37
Total formula weight3941.7
All*Total formula weight79190.3
*Water molecules are not included.

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PDB entries from 2024-09-11

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