9CUO

Crystal structure of CRBN with compound 3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Protein cereblon	polymer	113	12541.4	6	UniProt (Q96SW2) Pfam (PF03226)	Homo sapiens (human)
2	DA, G, L, MA, R... (E, A, B, F, C...)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	EA, H, M, NA, S... (E, A, B, F, C...)	(3S)-3-(3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidine-2,6-dione	non-polymer		259.3	6	Chemie (A1A0J)
4	FA, I, J, N, O... (E, A, B, F, C...)	SULFATE ION	non-polymer		96.1	13	Chemie (SO4)
5	AA, BA, CA, GA, HA... (D, E, A, B, F)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
6	RA, SA, TA, UA, VA... (A, B, C, D, E...)	water	water		18.0	305	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 319 - 427 (UniProt: Q96SW2)

PDB	External Database	Details
Ser 315	-	expression tag
Gly 316	-	expression tag
Ser 317	-	expression tag
Pro 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	75248.7
Non-Polymers*	Number of molecules	37
	Total formula weight	3941.7
All*	Total formula weight	79190.3

*Water molecules are not included.