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9CT5

HsSTING with diABZI and C53, together conformation

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Stimulator of interferon genes proteinpolymer36340246.08UniProt (Q86WV6)
Pfam (PF15009)
Homo sapiens (human)hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173
2I, K, N, P
(A, C, E, H)
1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamidenon-polymer490.94Chemie (9IM)
3J, L, M, O
(B, D, E, G)
1-[(2E)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-1,3-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1H-1,3-benzimidazole-5-carboxamidenon-polymer849.94Chemie (A1AZ0)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 344 (UniProt: Q86WV6)
PDBExternal DatabaseDetails
Gly 345-expression tag
Gly 346-expression tag
Ser 347-expression tag
Gly 348-expression tag
Gly 349-expression tag
Gly 350-expression tag
Ser 351-expression tag
Gly 352-expression tag
Gly 353-expression tag
Ser 354-expression tag
Ala 355-expression tag
Trp 356-expression tag
Ser 357-expression tag
His 358-expression tag
Pro 359-expression tag
Gln 360-expression tag
Phe 361-expression tag
Glu 362-expression tag
Lys 363-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight321968.0
Non-Polymers*Number of molecules8
Total formula weight5363.3
All*Total formula weight327331.3
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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