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9CT4

HsSTING with diABZI and C53, curved conformation

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Stimulator of interferon genes proteinpolymer36340246.04UniProt (Q86WV6)
Pfam (PF23417)
Pfam (PF15009)
Homo sapiens (human)hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173
2E, H
(A, D)
1-[(2E)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-1,3-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1H-1,3-benzimidazole-5-carboxamidenon-polymer849.92Chemie (A1AZ0)
3F, G
(A, C)
1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamidenon-polymer490.92Chemie (9IM)
Sequence modifications
A, B, C, D: 1 - 344 (UniProt: Q86WV6)
PDBExternal DatabaseDetails
Gly 345-expression tag
Gly 346-expression tag
Ser 347-expression tag
Gly 348-expression tag
Gly 349-expression tag
Gly 350-expression tag
Ser 351-expression tag
Gly 352-expression tag
Gly 353-expression tag
Ser 354-expression tag
Ala 355-expression tag
Trp 356-expression tag
Ser 357-expression tag
His 358-expression tag
Pro 359-expression tag
Gln 360-expression tag
Phe 361-expression tag
Glu 362-expression tag
Lys 363-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight160984.0
Non-Polymers*Number of molecules4
Total formula weight2681.6
All*Total formula weight163665.6
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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