9CRV
Native human GABAA receptor of beta2-alpha1-gamma2-beta2-alpha2 assembly
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Gamma-aminobutyric acid receptor subunit beta-2 | polymer | 488 | 56391.8 | 2 | UniProt (P47870) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit beta-2,GABAAR subunit beta-2 |
| 2 | B (B) | Gamma-aminobutyric acid receptor subunit alpha-1 | polymer | 429 | 48855.1 | 1 | UniProt (P14867) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit alpha-1,GABAAR subunit alpha-1 |
| 3 | C (C) | Gamma-aminobutyric acid receptor subunit gamma-2 | polymer | 436 | 50937.4 | 1 | UniProt (P18507) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit gamma-2,GABAAR subunit gamma-2 |
| 4 | E (E) | Gamma-aminobutyric acid receptor subunit alpha-2 | polymer | 423 | 48011.9 | 1 | UniProt (P47869) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit alpha-2,GABAAR subunit alpha-2 |
| 5 | F (K) | IgG2b Fab_1F4 Heavy Chain | polymer | 454 | 49811.0 | 1 | Mus musculus | ||
| 6 | G (L) | Kappa Fab_1F4 Light Chain | polymer | 213 | 23505.9 | 1 | Mus musculus | ||
| 7 | H, K (F, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | I, J, L (G, H, J) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 9 | M (M) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G07617FP) | |||
| 10 | N, R (A, D) | GAMMA-AMINO-BUTANOIC ACID | non-polymer | 103.1 | 2 | Chemie (ABU) | |||
| 11 | O, S (B, E) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 2 | Chemie (PIO) | |||
| 12 | P (B) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 1 | Chemie (POV) | |||
| 13 | Q (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 333905.1 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3843.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2680.7 | |
| All* | Total formula weight | 340429.3 |
