9CRF

Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Alpha (B.1.1.7) variant 1 open RBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, C, B)	Spike glycoprotein	polymer	1270	141006.2	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	AA, BA, CA, D, E... (e, f, g, E, F...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	26	In PDB GlyTouCan (G42666HT)
3	DA, K, U (h, L, W)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	3	In PDB GlyTouCan (G21290RB)
4	GA, HA, IA, JA, KA... (A, C, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	18	Chemie (NAG)

Sequence modifications

A, C, B: 1 - 1273 (UniProt: P0DTC2)

PDB	External Database	Details
-	His 69	deletion
-	Val 70	deletion
-	Tyr 144	deletion
Tyr 501	Asn 501	variant
Asp 570	Ala 570	variant
Gly 614	Asp 614	variant
His 681	Pro 681	variant
Ile 716	Thr 716	variant
Ala 982	Ser 982	variant
Ile 1068	Val 1068	variant
His 1118	Asp 1118	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	423018.5
Branched	Number of molecules	29
	Total formula weight	12746.1
Non-Polymers*	Number of molecules	18
	Total formula weight	3981.7
All*	Total formula weight	439746.3

*Water molecules are not included.