9CPP

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-17 and CC12.3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Spike protein S1	polymer	205	23104.9	1	UniProt (P0DTC2)	Severe acute respiratory syndrome coronavirus 2
2	B (F)	CC12.3 Fab heavy chain	polymer	220	23377.2	1		Homo sapiens
3	C (G)	CC12.3 Fab light chain	polymer	214	23344.9	1		Homo sapiens
4	D (H)	M22-17 Fab heavy chain	polymer	222	23485.5	1		Mus musculus
5	E (L)	M22-17 Fab light chain	polymer	220	24319.9	1		Mus musculus
6	F (B)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
7	G, H (A)	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT)

Sequence modifications

A: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	117632.3
Branched	Number of molecules	1
	Total formula weight	586.5
Non-Polymers*	Number of molecules	2
	Total formula weight	384.2
All*	Total formula weight	118603.1

*Water molecules are not included.