9CPH
Structural basis of BAK sequestration by MCL-1 and consequences for apoptosis initiation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 515 | 57152.8 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Bcl-2 homologous antagonist/killer | polymer | 21 | 2366.7 | 1 | UniProt (Q16611) | Homo sapiens (human) | Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| 3 | C (H) | Synthetic antibody, Fab fragment, Heavy Chain | polymer | 230 | 24534.4 | 1 | Homo sapiens (human) | ||
| 4 | D (L) | Synthetic antibody, Fab fragment, Light Chain | polymer | 214 | 23109.7 | 1 | Homo sapiens (human) | ||
| 5 | E (C) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 107163.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| All* | Total formula weight | 107505.9 |
