9CP9
Crystal structure of DHPS-3-dehydrogenase, HpsN H319A variant from Cupriavidus pinatubonensis in complex with substrate (R-DHPS) and NADH
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sulfopropanediol 3-dehydrogenase | polymer | 437 | 46924.1 | 2 | UniProt (Q46N53) | Cupriavidus pinatubonensis JMP134 | 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming),DHPS 3-dehydrogenase (sulfolactate forming) |
| 2 | C, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, I (A, B) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (94865921) PubChem (94865923) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (124432988) PubChem (140875346) PubChem (11250888) PubChem (12309341) PubChem (124934831) PubChem (124934833) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 4 | E, J (A, B) | (2R)-2,3-dihydroxypropane-1-sulfonic acid | non-polymer | 156.2 | 2 | Chemie (A1AZH) | |||
| 5 | F, G, K (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 459 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 436 (UniProt: Q46N53)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 319 | His 319 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93848.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2062.2 | |
| All* | Total formula weight | 95910.4 |
