9COH
Structure of the full-length Measles virus Fusion protein E170G E455G with mutated furin cleavage site in the pre-fusion conformation in amphipol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fusion glycoprotein F0 | polymer | 584 | 62620.0 | 3 | UniProt (Q786F3) Pfam (PF00523) | Measles virus strain Ichinose-B95a | |
| 2 | D, E (D, E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 3 | F (F) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 4 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | H, I, J, K, L (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 550 (UniProt: Q786F3)
| PDB | External Database | Details |
|---|---|---|
| Asn 109 | Arg 109 | engineered mutation |
| Asn 111 | Lys 111 | engineered mutation |
| Gly 170 | Glu 170 | engineered mutation |
| Gly 455 | Glu 455 | engineered mutation |
| Gly 551 | - | expression tag |
| Gly 552 | - | expression tag |
| Gly 553 | - | expression tag |
| Ser 554 | - | expression tag |
| Gly 555 | - | expression tag |
| Gly 556 | - | expression tag |
| Trp 557 | - | expression tag |
| Ser 558 | - | expression tag |
| His 559 | - | expression tag |
| Pro 560 | - | expression tag |
| Gln 561 | - | expression tag |
| Phe 562 | - | expression tag |
| Glu 563 | - | expression tag |
| Lys 564 | - | expression tag |
| Gly 565 | - | expression tag |
| Gly 566 | - | expression tag |
| Gly 567 | - | expression tag |
| Ser 568 | - | expression tag |
| Gly 569 | - | expression tag |
| Gly 570 | - | expression tag |
| Gly 571 | - | expression tag |
| Ser 572 | - | expression tag |
| Gly 573 | - | expression tag |
| Gly 574 | - | expression tag |
| Gly 575 | - | expression tag |
| Ser 576 | - | expression tag |
| Trp 577 | - | expression tag |
| Ser 578 | - | expression tag |
| His 579 | - | expression tag |
| Pro 580 | - | expression tag |
| Gln 581 | - | expression tag |
| Phe 582 | - | expression tag |
| Glu 583 | - | expression tag |
| Lys 584 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 187859.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1964.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 190930.7 |
