9COF
Structure of the full-length Measles virus Fusion protein E170G E455G in the pre-fusion conformation bound by [FIP-HRC]2-PEG11 in nanodisc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Fusion glycoprotein F2 | polymer | 112 | 12498.8 | 3 | UniProt (Q786F3) | Measles virus strain Ichinose-B95a | |
| 2 | B, D, F (B, D, F) | Fusion glycoprotein F1 | polymer | 472 | 50197.3 | 3 | UniProt (Q786F3) Pfam (PF00523) | Measles virus strain Ichinose-B95a | |
| 3 | G, H, I (P, Q, R) | [FIP-HRC]2-PEG11 | polymer | 4 | 503.5 | 3 | BIRD (PRD_002539) | synthetic construct | |
| 4 | J, M, P (G, J, M) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K, N, Q (H, K, N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | L, O, R (I, L, O) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 3 | In PDB GlyTouCan (G86851RC) | |||
| 7 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
B, D, F: 113 - 550 (UniProt: Q786F3)
| PDB | External Database | Details |
|---|---|---|
| Gly 170 | Glu 170 | engineered mutation |
| Gly 455 | Glu 455 | engineered mutation |
| Gly 551 | - | expression tag |
| Gly 552 | - | expression tag |
| Gly 553 | - | expression tag |
| Ser 554 | - | expression tag |
| Gly 555 | - | expression tag |
| Gly 556 | - | expression tag |
| Trp 557 | - | expression tag |
| Ser 558 | - | expression tag |
| His 559 | - | expression tag |
| Pro 560 | - | expression tag |
| Gln 561 | - | expression tag |
| Phe 562 | - | expression tag |
| Glu 563 | - | expression tag |
| Lys 564 | - | expression tag |
| Gly 565 | - | expression tag |
| Gly 566 | - | expression tag |
| Gly 567 | - | expression tag |
| Ser 568 | - | expression tag |
| Gly 569 | - | expression tag |
| Gly 570 | - | expression tag |
| Gly 571 | - | expression tag |
| Ser 572 | - | expression tag |
| Gly 573 | - | expression tag |
| Gly 574 | - | expression tag |
| Gly 575 | - | expression tag |
| Ser 576 | - | expression tag |
| Trp 577 | - | expression tag |
| Ser 578 | - | expression tag |
| His 579 | - | expression tag |
| Pro 580 | - | expression tag |
| Gln 581 | - | expression tag |
| Phe 582 | - | expression tag |
| Glu 583 | - | expression tag |
| Lys 584 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 189598.9 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4134.9 | |
| All* | Total formula weight | 193733.8 |
