9CO9

Local refinement of JN.1 spike/Nanosota-9 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Spike glycoprotein	polymer	1243	138330.8	2	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	C, D (D, E)	Nanosota-9	polymer	150	16311.6	2		Vicugna pacos

Sequence modifications

B, A: 1 - 1212 (UniProt: P0DTC2)

PDB	External Database	Details
Met 17	-	insertion
Pro 18	Asn 17	conflict
Phe 20	Thr 19	conflict
Asn 21	Thr 20	conflict
Leu 22	Arg 21	conflict
Ile 23	Thr 22	conflict
Thr 24	Gln 23	conflict
Thr 25	Leu 24	conflict
Thr 26	Pro 25	conflict
Gln 27	Pro 26	conflict
Ser 28	Ala 27	conflict
Leu 51	Ser 50	conflict
-	His 69	deletion
-	Val 70	deletion
Phe 126	Val 127	conflict
Asp 141	Gly 142	conflict
-	Tyr 144	deletion
Ser 155	Phe 157	conflict
Gly 156	Arg 158	conflict
-	Asn 211	deletion
Ile 209	Leu 212	conflict
Gly 210	Val 213	conflict
Phe 213	Leu 216	conflict
Asn 242	His 245	conflict
Asp 261	Ala 264	conflict
Val 329	Ile 332	conflict
His 336	Gly 339	conflict
Thr 353	Lys 356	conflict
Phe 368	Ser 371	conflict
Pro 370	Ser 373	conflict
Phe 372	Ser 375	conflict
Ala 373	Thr 376	conflict
Lys 400	Arg 403	conflict
Asn 402	Asp 405	conflict
Ser 405	Arg 408	conflict
Asn 414	Lys 417	conflict
Lys 437	Asn 440	conflict
His 442	Val 445	conflict
Ser 443	Gly 446	conflict
Asp 447	Asn 450	conflict
Trp 449	Leu 452	conflict
Ser 452	Leu 455	conflict
Lys 457	Asn 460	conflict
Asn 474	Ser 477	conflict
Lys 475	Thr 478	conflict
Lys 478	Asn 481	conflict
-	Val 483	deletion
Lys 480	Glu 484	conflict
Pro 482	Phe 486	conflict
Arg 494	Gln 498	conflict
Tyr 497	Asn 501	conflict
His 501	Tyr 505	conflict
Lys 550	Glu 554	conflict
Val 566	Ala 570	conflict
Gly 610	Asp 614	conflict
Ser 617	Pro 621	conflict
Tyr 651	His 655	conflict
Lys 675	Asn 679	conflict
Arg 677	Pro 681	conflict
Ala 678	Arg 682	conflict
Gly 679	Arg 683	conflict
Lys 760	Asn 764	conflict
Tyr 792	Asp 796	conflict
Pro 813	Phe 817	conflict
Pro 888	Ala 892	conflict
Pro 895	Ala 899	conflict
Phe 935	Ser 939	conflict
Pro 938	Ala 942	conflict
His 950	Gln 954	conflict
Lys 965	Asn 969	conflict
Pro 982	Lys 986	conflict
Pro 983	Val 987	conflict
Leu 1139	Pro 1143	conflict
Gly 1208	Trp 1212	conflict
Ser 1209	Pro 1213	conflict
Gly 1210	Trp 1214	conflict
Pro 1213	-	expression tag
Glu 1214	-	expression tag
Ala 1215	-	expression tag
Pro 1216	-	expression tag
Arg 1217	-	expression tag
Asp 1218	-	expression tag
Gly 1219	-	expression tag
Gln 1220	-	expression tag
Ala 1221	-	expression tag
Tyr 1222	-	expression tag
Val 1223	-	expression tag
Arg 1224	-	expression tag
Lys 1225	-	expression tag
Asp 1226	-	expression tag
Gly 1227	-	expression tag
Glu 1228	-	expression tag
Trp 1229	-	expression tag
Val 1230	-	expression tag
Leu 1231	-	expression tag
Leu 1232	-	expression tag
Ser 1233	-	expression tag
Thr 1234	-	expression tag
Phe 1235	-	expression tag
Leu 1236	-	expression tag
Gly 1237	-	expression tag
His 1238	-	expression tag
His 1239	-	expression tag
His 1240	-	expression tag
His 1241	-	expression tag
His 1242	-	expression tag
His 1243	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	309284.8
All*	Total formula weight	309284.8

*Water molecules are not included.