9CMT
The crystal structure of HP1alpha CSD-Agno complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E (A, B, D, E) | Chromobox protein homolog 5 | polymer | 65 | 7392.4 | 4 | UniProt (P45973) Pfam (PF01393) | Homo sapiens (human) | Antigen p25,Heterochromatin protein 1 homolog alpha,HP1 alpha |
| 2 | C, F (C, F) | Agnoprotein | polymer | 16 | 1866.2 | 2 | UniProt (P03086) | JC polyomavirus | Agno |
| 3 | G, H (C, F) | 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID | non-polymer | 376.3 | 2 | Chemie (F6Z) |
Sequence modifications
A, B, D, E: 112 - 176 (UniProt: P45973)
| PDB | External Database | Details |
|---|---|---|
| Glu 112 | Asp 112 | conflict |
| Ser 133 | Cys 133 | engineered mutation |
| Ser 145 | Thr 145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 33302.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 752.6 | |
| All* | Total formula weight | 34054.7 |
