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9CMH

Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Claudin-4polymer21122234.31UniProt (O14493)
Pfam (PF00822)
Homo sapiens (human)Clostridium perfringens enterotoxin receptor,CPE-R,CPE-receptor,Williams-Beuren syndrome chromosomal region 8 protein
2B
(B)
Heat-labile enterotoxin B chainpolymer29933000.61UniProt (P01558)
Pfam (PF03505)
Clostridium perfringens
Sequence modifications
A: 1 - 209 (UniProt: O14493)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
B: 26 - 319 (UniProt: P01558)
PDBExternal DatabaseDetails
Gly 320-expression tag
Leu 321-expression tag
Val 322-expression tag
Pro 323-expression tag
Arg 324-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55234.9
All*Total formula weight55234.9
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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