9CMH

Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Claudin-4	polymer	211	22234.3	1	UniProt (O14493) Pfam (PF00822) In PDB	Homo sapiens (human)	Clostridium perfringens enterotoxin receptor,CPE-R,CPE-receptor,Williams-Beuren syndrome chromosomal region 8 protein
2	B	Heat-labile enterotoxin B chain	polymer	299	33000.6	1	UniProt (P01558) Pfam (PF03505) In PDB	Clostridium perfringens

Sequence modifications

A: 1 - 209 (UniProt: O14493)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 26 - 319 (UniProt: P01558)

PDB	External Database	Details
Gly 320	-	expression tag
Leu 321	-	expression tag
Val 322	-	expression tag
Pro 323	-	expression tag
Arg 324	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55234.9
All*	Total formula weight	55234.9

*Water molecules are not included.