9CKN
Histidine-covalent alpha-helical peptide (compound 6) targeting hMcl-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17850.3 | 2 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | C, D (D, E) | Helical Peptide | polymer | 14 | 1596.8 | 2 | synthetic construct | ||
| 3 | E, F, G, H (A, B, D, E) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 172 - 323 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 168 | - | expression tag |
| Ser 169 | - | expression tag |
| His 170 | - | expression tag |
| Met 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 38894.3 | |
| All* | Total formula weight | 38894.3 |
