9CKG
Crystal structure of SMYD2 active site mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-lysine methyltransferase SMYD2 | polymer | 433 | 49684.0 | 1 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) | Homo sapiens (human) | HSKM-B,Histone methyltransferase SMYD2,Lysine N-methyltransferase 3C,SET and MYND domain-containing protein 2 |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 3 | C, D, E (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F, G (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | I (A) | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
| 7 | J (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) |
Sequence modifications
A: 1 - 433 (UniProt: Q9NRG4)
| PDB | External Database | Details |
|---|---|---|
| Ala 184 | Phe 184 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49684.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1125.3 | |
| All* | Total formula weight | 50809.3 |
