9CKC
Crystal structure of SMYD2 in complex with two PARP1 peptides
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-lysine methyltransferase SMYD2 | polymer | 433 | 49832.2 | 2 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) | Homo sapiens (human) | HSKM-B,Histone methyltransferase SMYD2,Lysine N-methyltransferase 3C,SET and MYND domain-containing protein 2 |
| 2 | C, D, E, F (C, D, E, F) | Poly [ADP-ribose] polymerase 1, processed C-terminus | polymer | 13 | 1362.7 | 4 | UniProt (P09874) | Homo sapiens | Poly [ADP-ribose] polymerase 1,89-kDa form |
| 3 | G, K (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 4 | H, I, J, L, M... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 420 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 433 (UniProt: Q9NRG4)
| PDB | External Database | Details |
|---|---|---|
| Glu 165 | Gly 165 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 105115.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1161.3 | |
| All* | Total formula weight | 106276.3 |
