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9CK0

Cocrystal of PPARg LBD and NFKBIB / IKBB peptide with agonist GW1929

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APeroxisome proliferator-activated receptor gammapolymer27631506.61UniProt (P37231)
Pfam (PF00104)
In PDB
Homo sapiens (human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2BNF-kappa-B inhibitor betapolymer232425.91UniProt (Q15653)
In PDB
Homo sapiensNF-kappa-BIB,I-kappa-B-beta,IkB-B,IkB-beta,IkappaBbeta,Thyroid receptor-interacting protein 9,TR-interacting protein 9,TRIP-9
3A(2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acidnon-polymer495.61Chemie (EDK)
Sequence modifications
A: 203 - 477 (UniProt: P37231)
PDBExternal DatabaseDetails
Gly 202-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight33932.5
Non-Polymers*Number of molecules1
Total formula weight495.6
All*Total formula weight34428.1
*Water molecules are not included.

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PDB entries from 2024-09-18

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