9CJ5

Unphosphorylated human p38 alpha bound to pexmetinib

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mitogen-activated protein kinase 14	polymer	360	41343.2	1	UniProt (Q16539) Pfam (PF00069)	Homo sapiens (human)	MAP kinase 14,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSAID-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
2	B, C, D, G (A)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
3	E (A)	Pexmetinib	non-polymer		556.6	1	Chemie (A1AWV)
4	F (A)	1,3-PROPANDIOL	non-polymer		76.1	1	Chemie (PDO)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41343.2
Non-Polymers*	Number of molecules	6
	Total formula weight	881.0
All*	Total formula weight	42224.2

*Water molecules are not included.