9CJ3
Dual phosphorylated human p38 alpha bound to pexmetinib
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 360 | 41503.2 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 14,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSAID-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C, D, F, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G, J (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 6 | I (A) | 1,3-PROPANDIOL | non-polymer | 76.1 | 1 | Chemie (PDO) | |||
| 7 | K (A) | Pexmetinib | non-polymer | 556.6 | 1 | Chemie (A1AWV) | |||
| 8 | L (A) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41503.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1225.4 | |
| All* | Total formula weight | 42728.6 |
