9CIQ
Crystal structure of human polymerase eta with incoming threofuranosyl thymine nucleoside triphosphate opposite template dA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 435 | 48617.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | B (T) | DNA (5'-D(*CP*AP*TP*AP*AP*TP*GP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3646.4 | 1 | synthetic construct | ||
| 3 | C (P) | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3') | polymer | 8 | 2426.6 | 1 | synthetic construct | ||
| 4 | D (A) | [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate | non-polymer | 468.1 | 1 | Chemie (A1ANT) | |||
| 5 | E, F (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | G, H (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | I, J, K (A, T, P) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54690.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 760.5 | |
| All* | Total formula weight | 55451.3 |
