9CDZ
Crystal Structure of MDM2-Peptide Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | E3 ubiquitin-protein ligase Mdm2 | polymer | 108 | 12332.1 | 2 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 2 | B, D (B, D) | Peptide | polymer | 16 | 1814.9 | 2 | synthetic construct | ||
| 3 | E, F (A, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, C: 13 - 120 (UniProt: Q00987)
| PDB | External Database | Details |
|---|---|---|
| Ala 64 | Glu 69 | engineered mutation |
| Ala 65 | Lys 70 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 28294.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 28340.1 |
