Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Fibroblast growth factor receptor 3 | polymer | 312 | 35107.4 | 3 | UniProt (P22607) In PDB | Homo sapiens (human) | FGFR-3 |
| 2 | A, B, C | (3P)-5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-3-{6-[6-(methanesulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl]pyridin-3-yl}-1H-indazole | non-polymer | 559.5 | 3 | Chemie (A1AV2) | |||
| 3 | A, B, C | GLYCEROL | non-polymer | 92.1 | 16 | Chemie (GOL) | |||
| 4 | B, C | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B, C: 448 - 759 (UniProt: P22607)
| PDB | External Database | Details |
|---|---|---|
| Ala 482 | Cys 482 | engineered mutation |
| Ser 582 | Cys 582 | engineered mutation |
| Glu 650 | Lys 650 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 105322.1 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 3536.2 | |
| All* | Total formula weight | 108858.2 |
