Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Fibroblast growth factor receptor 1 | polymer | 308 | 35078.3 | 2 | UniProt (P11362) In PDB | Homo sapiens (human) | FGFR-1,Basic fibroblast growth factor receptor 1,BFGFR,bFGF-R-1,Fms-like tyrosine kinase 2,FLT-2,N-sam,Proto-oncogene c-Fgr |
| 2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | A, B | (3P)-5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-3-{6-[6-(methanesulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl]pyridin-3-yl}-1H-indazole | non-polymer | 559.5 | 2 | Chemie (A1AV2) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, B: 458 - 765 (UniProt: P11362)
| PDB | External Database | Details |
|---|---|---|
| Ala 488 | Cys 488 | engineered mutation |
| Ser 584 | Cys 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70156.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2554.0 | |
| All* | Total formula weight | 72710.5 |
