9CCC
Crystal structure of human dihydroorotate dehydrogenase with new alkyne ligand
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 368 | 39943.6 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 3 | C (A) | N-{4-[(3-aminophenyl)ethynyl]phenyl}acetamide | non-polymer | 250.3 | 1 | Chemie (A1AVV) | |||
| 4 | D, H (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | E, F, J (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | I (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 8 | K (A) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Ser 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39943.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1366.6 | |
| All* | Total formula weight | 41310.2 |
