9CC2
Cryo-EM structure of mouse PI(4,5)P2-bound TRPML1 channel at 2.46 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Mucolipin-1 | polymer | 580 | 65573.6 | 4 | UniProt (Q99J21) Pfam (PF21381) Pfam (PF00520) Pfam (PF08016) | Mus musculus (house mouse) | Mucolipidin,Transient receptor potential-mucolipin 1,TRPML1 |
| 2 | E, F, G, H (E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | I, L, N, P (A, B, C, D) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 4 | Chemie (PIO) | |||
| 4 | J, K, M, O (A, B, C, D) | sphingomyelin | non-polymer | 814.2 | 4 | Chemie (FO4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 262294.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 6243.2 | |
| All* | Total formula weight | 270235.3 |
