9CBP
Methionine synthase from Thermus thermophilus HB8, Homocysteine, Folate, and Cobalamin Domains, Pre-Catalytic State (Pre-Hcy-on)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine synthase | polymer | 874 | 95487.3 | 1 | UniProt (Q5SKM5) Pfam (PF02574) Pfam (PF00809) Pfam (PF02607) Pfam (PF02310) | Thermus thermophilus HB8 | 5-methyltetrahydrofolate--homocysteine methyltransferase |
| 2 | B, E, F, G, H... (A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 3 | C (A) | 2-AMINO-4-MERCAPTO-BUTYRIC ACID | non-polymer | 135.2 | 1 | Chemie (HCS) | |||
| 4 | D, L (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | K (A) | COBALAMIN | non-polymer | 1330.4 | 1 | Chemie (B12) | |||
| 6 | M (A) | PROPANE | non-polymer | 44.1 | 1 | Chemie (TME) | |||
| 7 | N (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 8 | O (A) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 1 - 874 (UniProt: Q5SKM5)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Phe 110 | engineered mutation |
| Ala 123 | Glu 123 | engineered mutation |
| Ala 124 | Glu 124 | engineered mutation |
| Ala 296 | Tyr 296 | engineered mutation |
| Ala 651 | Asp 651 | engineered mutation |
| Ala 652 | Pro 652 | engineered mutation |
| Ala 653 | Gly 653 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 95487.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2324.2 | |
| All* | Total formula weight | 97811.5 |
