9CBO
Methionine synthase from Thermus thermophilus HB8, Folate and Cobalamin Domains, Pre-Catalytic Conformation (Pre-Fol-on)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Methionine synthase | polymer | 511 | 56693.6 | 6 | UniProt (Q5SKM5) Pfam (PF00809) Pfam (PF02607) Pfam (PF02310) | Thermus thermophilus HB8 | 5-methyltetrahydrofolate--homocysteine methyltransferase |
| 2 | G, M, O, T, V... (A, B, C, D, E...) | CO-METHYLCOBALAMIN | non-polymer | 1344.4 | 6 | Chemie (COB) | |||
| 3 | H, I, J, N, P... (A, B, C, D, E...) | GLYCEROL | non-polymer | 92.1 | 11 | Chemie (GOL) PubChem (753) | |||
| 4 | K, L (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) PubChem (3777159) | |||
| 5 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 364 - 874 (UniProt: Q5SKM5)
| PDB | External Database | Details |
|---|---|---|
| Ala 759 | Asp 759 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 340161.7 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 9323.6 | |
| All* | Total formula weight | 349485.3 |
