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9CAC

Cryo-EM structure of the RuvBL lobe of the native human TIP60 complex (composite structure)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E1A-binding protein p400polymer3159343867.31UniProt (Q96L91)Homo sapiens (human)CAG repeat protein 32,Domino homolog,hDomino,Trinucleotide repeat-containing gene 12 protein,p400 kDa SWI2/SNF2-related protein
2B
(B)
Vacuolar protein sorting-associated protein 72 homologpolymer36440658.41UniProt (Q15906)Homo sapiens (human)Protein YL-1,Transcription factor-like 1
3C
(C)
Enhancer of polycomb homolog 1polymer83693589.21UniProt (Q9H2F5)Homo sapiens (human)
4D, F, H
(E, G, I)
RuvB-like 1polymer45650296.93UniProt (Q9Y265)Homo sapiens (human)49 kDa TATA box-binding protein-interacting protein,49 kDa TBP-interacting protein,54 kDa erythrocyte cytosolic protein,ECP-54,INO80 complex subunit H,Nuclear matrix protein 238,NMP 238,Pontin 52,TIP49a,TIP60-associated protein 54-alpha,TAP54-alpha
5E, G, I
(F, H, J)
RuvB-like 2polymer46351222.53UniProt (Q9Y230)Homo sapiens (human)48 kDa TATA box-binding protein-interacting protein,48 kDa TBP-interacting protein,51 kDa erythrocyte cytosolic protein,ECP-51,INO80 complex subunit J,Repressing pontin 52,Reptin 52,TIP49b,TIP60-associated protein 54-beta,TAP54-beta
6J, K
(K, L)
Actin, cytoplasmic 1polymer37541782.72UniProt (P60709)Homo sapiens (human)Beta-actin
7L
(M)
Actin-like protein 6Apolymer42947509.81UniProt (O96019)Homo sapiens (human)53 kDa BRG1-associated factor A,Actin-related protein Baf53a,ArpNbeta,BRG1-associated factor 53A,BAF53A,INO80 complex subunit K
8M
(N)
DNA methyltransferase 1-associated protein 1polymer46753090.71UniProt (Q9NPF5)Homo sapiens (human)DNMAP1,DNMT1-associated protein 1
9N, P, R, T, V...
(E, F, G, H, I...)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.27Chemie (ADP)
10AA, CA, O, Q, S...
(L, M, E, F, G...)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
11BA
(M)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight966838.8
Non-Polymers*Number of molecules16
Total formula weight3692.0
All*Total formula weight970530.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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