9C7W
human OC43 Main Protease (1-303) in complex with potent inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ORF1ab polyprotein | polymer | 298 | 32962.7 | 4 | UniProt (U3M6R3) Pfam (PF05409) UniProt (by SIFTS) (U3M7V0) | Human coronavirus OC43 | |
| 2 | E, F, G, H (A, B, C, D) | (8S)-3-(4,4-difluorocyclohexyl)-5-(pyrimidin-2-yl)pyrazolo[1,5-a]pyrimidine | non-polymer | 315.3 | 4 | Chemie (A1AUY) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 662 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 298 (UniProt: U3M6R3)
| PDB | External Database | Details |
|---|---|---|
| Leu 194 | Pro 3440 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 131850.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1261.3 | |
| All* | Total formula weight | 133112.2 |
