9C7R
Diheteromeric GluN1/GluN2A (M817V) in digitonin complexed with glycine, glutamate, and GNE-4123
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor ionotropic, NMDA 1, Green fluorescent protein chimera | polymer | 1108 | 124759.2 | 2 | UniProt (P35439) UniProt (P42212) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF01353) | Rattus norvegicus (Norway rat) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2A, Green fluorescent protein chimera | polymer | 1127 | 126455.3 | 2 | UniProt (Q00959) UniProt (P42212) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF01353) | Rattus norvegicus (Norway rat) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A |
| 3 | E, F, G, H, I... (E, F, G, H, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 20 | In PDB GlyTouCan (G42666HT) | |||
| 4 | AA, BA, CA, DA, EA... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
A, C: 1 - 847 (UniProt: P35439)
A, C: 859 - 1095 (UniProt: P42212)
B, D: 1 - 877 (UniProt: Q00959)
B, D: 878 - 1114 (UniProt: P42212)
| PDB | External Database | Details |
|---|---|---|
| Leu 848 | - | linker |
| Val 849 | - | linker |
| Pro 850 | - | linker |
| Arg 851 | - | linker |
| Gly 852 | - | linker |
| Ser 853 | - | linker |
| Ala 854 | - | linker |
| Ala 855 | - | linker |
| Ala 856 | - | linker |
| Ala 857 | - | linker |
| Val 858 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 921 | Phe 64 | conflict |
| Thr 922 | Ser 65 | conflict |
| Lys 1063 | Ala 206 | conflict |
| Leu 1088 | His 231 | conflict |
| Ser 1096 | - | expression tag |
| Gly 1097 | - | expression tag |
| Leu 1098 | - | expression tag |
| Arg 1099 | - | expression tag |
| Ser 1100 | - | expression tag |
| His 1101 | - | expression tag |
| His 1102 | - | expression tag |
| His 1103 | - | expression tag |
| His 1104 | - | expression tag |
| His 1105 | - | expression tag |
| His 1106 | - | expression tag |
| His 1107 | - | expression tag |
| His 1108 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 758 | Ser 758 | conflict |
| Val 817 | Met 817 | conflict |
| - | Gly 866 | deletion |
| Gly 866 | - | linker |
| Leu 867 | - | linker |
| Val 868 | - | linker |
| Pro 869 | - | linker |
| Arg 870 | - | linker |
| Gly 871 | - | linker |
| Ser 872 | - | linker |
| Ala 873 | - | linker |
| Ala 874 | - | linker |
| Ala 875 | - | linker |
| Ala 876 | - | linker |
| Val 877 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 940 | Phe 64 | conflict |
| Thr 941 | Ser 65 | conflict |
| Lys 1082 | Ala 206 | conflict |
| Leu 1107 | His 231 | conflict |
| Ser 1115 | - | expression tag |
| Gly 1116 | - | expression tag |
| Leu 1117 | - | expression tag |
| Arg 1118 | - | expression tag |
| Ser 1119 | - | expression tag |
| Trp 1120 | - | expression tag |
| Ser 1121 | - | expression tag |
| His 1122 | - | expression tag |
| Pro 1123 | - | expression tag |
| Gln 1124 | - | expression tag |
| Phe 1125 | - | expression tag |
| Glu 1126 | - | expression tag |
| Lys 1127 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 502429.1 | |
| Branched | Number of molecules | 20 |
| Total formula weight | 8488.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 514235.2 |
