9C56
Crystal structure of human PTPN2 in complex with allosteric inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein phosphatase non-receptor type 2 | polymer | 315 | 36715.6 | 1 | UniProt (P17706) Pfam (PF00102) In PDB | Homo sapiens (human) | T-cell protein-tyrosine phosphatase,TCPTP |
| 2 | A | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE | non-polymer | 741.4 | 1 | Chemie (FRJ) | |||
| 3 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A: 1 - 314 (UniProt: P17706)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36715.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 741.4 | |
| All* | Total formula weight | 37457.1 |
