9C1T

Crystal structure of integrin beta-3 tail bound to the FERM-folded talin head domain with a D397R mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Integrin beta-3, Talin-1	polymer	411	47449.6	1	UniProt (P26039) Pfam (PF16511) Pfam (PF00373) Pfam (PF02174)	Homo sapiens (human)
2	B (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	C (A)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: -10 - 0 (PDB: 9C1T)
A: 1 - 430 (UniProt: P26039)

PDB	External Database	Details
-	Asp 139	deletion
-	Glu 140	deletion
-	Gly 141	deletion
-	Thr 142	deletion
-	Gly 143	deletion
-	Thr 144	deletion
-	Leu 145	deletion
-	Arg 146	deletion
-	Lys 147	deletion
-	Asp 148	deletion
-	Lys 149	deletion
-	Thr 150	deletion
-	Leu 151	deletion
-	Leu 152	deletion
-	Arg 153	deletion
-	Asp 154	deletion
-	Glu 155	deletion
-	Lys 156	deletion
-	Lys 157	deletion
-	Met 158	deletion
-	Glu 159	deletion
-	Lys 160	deletion
-	Leu 161	deletion
-	Lys 162	deletion
-	Gln 163	deletion
-	Lys 164	deletion
-	Leu 165	deletion
-	His 166	deletion
-	Thr 167	deletion
-	Asp 168	deletion
Arg 397	Asp 397	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47449.6
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	47545.7

*Water molecules are not included.