9C1A

Crystal structure of GDP-bound human M-RAS protein in crystal form I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ras-related protein M-Ras	polymer	193	22253.3	1	UniProt (O14807) Pfam (PF00071)	Homo sapiens (human)	Ras-related protein R-Ras3
2	B, G (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	C (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
4	D, E, F (A)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	H (A)	water	water		18.0	217	Chemie (HOH)

Sequence modifications

A: 1 - 178 (UniProt: O14807)

PDB	External Database	Details
Met -14	-	initiating methionine
Gly -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22253.3
Non-Polymers*	Number of molecules	6
	Total formula weight	768.1
All*	Total formula weight	23021.4

*Water molecules are not included.