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9C0H

Phosphorylated human NKCC1 in complex with bumetanide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Solute carrier family 12 member 2polymer1212131743.42UniProt (P55011)
Pfam (PF08403)
Pfam (PF00324)
Pfam (PF03522)
Homo sapiens (human)Basolateral Na-K-Cl symporter,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
2C, G
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
3D, H
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E, I
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
5F, J
(A, B)
3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acidnon-polymer364.42Chemie (82U)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight263486.8
Non-Polymers*Number of molecules8
Total formula weight923.9
All*Total formula weight264410.7
*Water molecules are not included.

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PDB entries from 2025-06-25

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