9BXY
CRYSTAL STRUCTURE OF HIV-1 LM/HS CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH DL-III-117
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 LM/HS clade A/E CRF01 gp120 core | polymer | 355 | 39452.7 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B, C, D, E, F... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 3 | K (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 4 | L (A) | (3S,5R)-1-[4-(1-carbamimidoyl-L-prolyl)piperazine-1-carbonyl]-N-(4-chloro-3-fluorophenyl)-5-(hydroxymethyl)piperidine-3-carboxamide | non-polymer | 538.0 | 1 | Chemie (A1ATE) | |||
| 5 | M (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Val 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Tyr 61 | His 18 | engineered mutation |
| His 105 | Gln 62 | engineered mutation |
| Ile 108 | Val 65 | engineered mutation |
| Ser 375 | His 242 | engineered mutation |
| Asp 474 | Asn 335 | engineered mutation |
| Met 475 | Ile 336 | engineered mutation |
| Arg 476 | Lys 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39452.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2767.2 | |
| All* | Total formula weight | 42219.9 |
