9BUH
Cryo-EM structure of respiratory supercomplex I III IV
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome c oxidase subunit 6C | polymer | 74 | 8626.2 | 1 | Pfam (PF02937) UniProt (by SIFTS) (P04038) | Sus scrofa (pig) | |
| 2 | B (t) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 137 | 16487.9 | 1 | UniProt (F1SCH1) Pfam (PF05676) | Sus scrofa (pig) | |
| 3 | C (F) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 123 | 13349.0 | 1 | UniProt (A0A4X1THU2) Pfam (PF10276) | Sus scrofa (pig) | |
| 4 | D (K) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17162.4 | 1 | UniProt (F1SQP4) Pfam (PF05071) | Sus scrofa (pig) | |
| 5 | E (U) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 357 | 40476.1 | 1 | UniProt (F1SIS9) Pfam (PF01712) | Sus scrofa (pig) | |
| 6 | F (Z) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 114 | 12857.6 | 1 | UniProt (A0A8D0INK7) Pfam (PF08122) | Sus scrofa (pig) | Complex I-B12,NADH-ubiquinone oxidoreductase B12 subunit |
| 7 | G (a) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 189 | 21587.0 | 1 | UniProt (F1SGC6) Pfam (PF09781) | Sus scrofa (pig) | |
| 8 | H (i) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39077.5 | 1 | UniProt (O79875) Pfam (PF00361) Pfam (PF06444) | Sus scrofa (pig) | NADH dehydrogenase subunit 2 |
| 9 | I (m) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19021.3 | 1 | UniProt (O79882) Pfam (PF00499) | Sus scrofa (pig) | |
| 10 | J (p) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 221 | 26347.2 | 1 | UniProt (K7GSE5) Pfam (PF05347) | Sus scrofa (pig) | Complex I-B22,NADH-ubiquinone oxidoreductase B22 subunit |
| 11 | K (q) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 51859.4 | 1 | UniProt (O79881) Pfam (PF01059) Pfam (PF00361) | Sus scrofa (pig) | NADH dehydrogenase subunit 4 |
| 12 | L, XB (Aa, z) | Cytochrome b-c1 complex subunit 8 | polymer | 82 | 9784.3 | 2 | UniProt (A0A8D0SHY6) Pfam (PF02939) | Sus scrofa (pig) | |
| 13 | BA, M (Ab, 0) | Cytochrome b-c1 complex subunit 6, mitochondrial | polymer | 91 | 10685.8 | 2 | UniProt (A0A8D1JI21) Pfam (PF02320) | Sus scrofa (pig) | |
| 14 | CA, N (Ac, 1) | Ubiquinol-cytochrome c reductase complex 7.2 kDa protein | polymer | 64 | 7412.5 | 2 | UniProt (A0A8D1J3N6) Pfam (PF05365) | Sus scrofa (pig) | cytochrome b-c1 complex subunit 9 |
| 15 | EA, O (Ad, 3) | Cytochrome b-c1 complex subunit 10 | polymer | 56 | 6560.7 | 2 | UniProt (F1SDI2) Pfam (PF08997) | Sus scrofa (pig) | |
| 16 | P (Ag) | Cytochrome c oxidase subunit 8 | polymer | 70 | 7615.9 | 1 | UniProt (A1XQT4) Pfam (PF02285) | Sus scrofa (pig) | |
| 17 | Q (Ah) | Cytochrome c oxidase subunit 7A1, mitochondrial | polymer | 80 | 9028.5 | 1 | UniProt (Q8SPJ9) Pfam (PF02238) | Sus scrofa (pig) | |
| 18 | R (Ai) | Cytochrome c oxidase subunit 7B | polymer | 80 | 9169.5 | 1 | UniProt (A0A287BJ57) Pfam (PF05392) | Sus scrofa (pig) | |
| 19 | S (Aj) | Cytochrome c oxidase subunit 7C, mitochondrial | polymer | 63 | 7358.7 | 1 | UniProt (Q1W0Y2) Pfam (PF02935) | Sus scrofa (pig) | |
| 20 | T (Ak) | Cytochrome c oxidase subunit 1 | polymer | 514 | 56992.7 | 1 | UniProt (O79876) Pfam (PF00115) | Sus scrofa (pig) | |
| 21 | U (Al) | Cytochrome c oxidase subunit 2 | polymer | 228 | 26203.6 | 1 | UniProt (P50667) Pfam (PF02790) Pfam (PF00116) | Sus scrofa (pig) | Cytochrome c oxidase polypeptide II |
| 22 | V (Am) | Cytochrome c oxidase subunit 3 | polymer | 261 | 29753.4 | 1 | UniProt (Q35916) Pfam (PF00510) | Sus scrofa (pig) | |
| 23 | W (An) | Cytochrome c oxidase subunit 4 | polymer | 169 | 19670.7 | 1 | UniProt (A0A4X1T8J9) Pfam (PF02936) | Sus scrofa (pig) | |
| 24 | X (Ao) | Cytochrome c oxidase subunit 5A, mitochondrial | polymer | 152 | 16771.2 | 1 | UniProt (F1SJ34) Pfam (PF02284) | Sus scrofa (pig) | |
| 25 | Y (Ap) | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 129 | 13801.8 | 1 | UniProt (Q5S3G4) Pfam (PF01215) | Sus scrofa (pig) | |
| 26 | Z (Aq) | Cytochrome c oxidase subunit 6A2 | polymer | 97 | 10876.4 | 1 | UniProt (A0A287AEB7) Pfam (PF02046) | Sus scrofa (pig) | |
| 27 | AA (Ar) | Cytochrome c oxidase subunit | polymer | 86 | 10170.4 | 1 | UniProt (A0A8D0W345) Pfam (PF02297) | Sus scrofa (pig) | |
| 28 | AC, BC, DA, FA (2, 4, Ae, Af) | Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | polymer | 299 | 32174.7 | 4 | UniProt (F1RNZ1) Pfam (PF09165) Pfam (PF02921) Pfam (PF00355) | Sus scrofa (pig) | |
| 29 | GA, SB (5, u) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 480 | 52756.3 | 2 | UniProt (A0A8D0PK14) Pfam (PF00675) Pfam (PF05193) | Sus scrofa (pig) | |
| 30 | HA, TB (6, v) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 453 | 48262.4 | 2 | UniProt (F1RPD2) Pfam (PF05193) Pfam (PF00675) | Sus scrofa (pig) | |
| 31 | IA, UB (7, w) | Cytochrome b | polymer | 379 | 42840.7 | 2 | UniProt (Q1HBG9) Pfam (PF00033) Pfam (PF00032) | Sus scrofa (pig) | |
| 32 | JA, VB (8, x) | Cytochrome c1 | polymer | 326 | 35488.9 | 2 | UniProt (A0A287AZF9) Pfam (PF02167) | Sus scrofa (pig) | |
| 33 | KA, WB (9, y) | Cytochrome b-c1 complex subunit 7 | polymer | 111 | 13587.5 | 2 | UniProt (A0A286ZPR8) Pfam (PF02271) | Sus scrofa (pig) | |
| 34 | LA (B) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 464 | 50637.8 | 1 | UniProt (A0A4X1SZP7) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Sus scrofa (pig) | |
| 35 | MA (C) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 469 | 53282.2 | 1 | UniProt (A0A480XQH6) Pfam (PF00346) | Sus scrofa (pig) | Complex I-49kD,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 36 | NA (D) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 264 | 30241.4 | 1 | UniProt (A0A286ZNN4) Pfam (PF00329) | Sus scrofa (pig) | Complex I-30kD,NADH-ubiquinone oxidoreductase 30 kDa subunit |
| 37 | OA (E) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 249 | 27439.5 | 1 | UniProt (A0A4X1VRV3) Pfam (PF01257) | Sus scrofa (pig) | |
| 38 | PA (G) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 727 | 79627.4 | 1 | UniProt (A0A287ARY3) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) | Sus scrofa (pig) | |
| 39 | QA (H) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | polymer | 212 | 23893.3 | 1 | UniProt (A0A286ZUN9) Pfam (PF12838) | Sus scrofa (pig) | Complex I-23kD,NADH-ubiquinone oxidoreductase 23 kDa subunit |
| 40 | RA (I) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | polymer | 258 | 28500.2 | 1 | UniProt (A0A4X1VVS8) Pfam (PF01058) | Sus scrofa (pig) | |
| 41 | SA (J) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 175 | 19718.5 | 1 | UniProt (G8IFA6) Pfam (PF04800) | Sus scrofa (pig) | Complex I-18 kDa,NADH-ubiquinone oxidoreductase 18 kDa subunit |
| 42 | TA (L) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | polymer | 372 | 42066.7 | 1 | UniProt (F1SL07) Pfam (PF01370) | Sus scrofa (pig) | Complex I-39kD,NADH-ubiquinone oxidoreductase 39 kDa subunit |
| 43 | UA (M) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 113 | 12648.6 | 1 | UniProt (A0A8W4F7N8) Pfam (PF07347) | Sus scrofa (pig) | |
| 44 | VA (N) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1 | polymer | 116 | 13321.6 | 1 | UniProt (A0A8D0UWW0) Pfam (PF04716) | Sus scrofa (pig) | |
| 45 | WA, YB (O, X) | Acyl carrier protein | polymer | 156 | 17308.2 | 2 | UniProt (A0A8D1WW27) Pfam (PF00550) | Sus scrofa (pig) | |
| 46 | XA (P) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 99 | 11099.8 | 1 | UniProt (A0A8D1FN21) Pfam (PF05047) | Sus scrofa (pig) | |
| 47 | YA (Q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 154 | 17890.0 | 1 | UniProt (A0A8D0Z0K9) Pfam (PF05347) | Sus scrofa (pig) | Complex I-B14,NADH-ubiquinone oxidoreductase B14 subunit |
| 48 | ZA (S) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8034.4 | 1 | UniProt (A0A8D0TJQ4) Pfam (PF15879) | Sus scrofa (pig) | |
| 49 | AB (T) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 169 | 18319.0 | 1 | UniProt (A0A8D0Q6N1) Pfam (PF14987) | Sus scrofa (pig) | Complex I-B9,NADH-ubiquinone oxidoreductase B9 subunit |
| 50 | BB (V) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 141 | 14686.9 | 1 | UniProt (I3LGM4) Pfam (PF02466) | Sus scrofa (pig) | |
| 51 | CB (W) | NADH:ubiquinone oxidoreductase subunit A13 | polymer | 144 | 16911.6 | 1 | UniProt (A0A8D0K655) Pfam (PF06212) | Sus scrofa (pig) | |
| 52 | DB (Y) | NADH:ubiquinone oxidoreductase subunit B2 | polymer | 105 | 11939.4 | 1 | UniProt (A0A8D1G9F4) Pfam (PF14813) | Sus scrofa (pig) | |
| 53 | EB (b) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 188 | 21904.1 | 1 | UniProt (A0A480KM09) Pfam (PF09782) | Sus scrofa (pig) | Complex I-B17,NADH-ubiquinone oxidoreductase B17 subunit |
| 54 | FB (c) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 186 | 21702.5 | 1 | UniProt (F1RWL7) Pfam (PF05821) | Sus scrofa (pig) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 55 | GB (d) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 176 | 20944.8 | 1 | UniProt (A0A8D0R7A9) Pfam (PF10249) | Sus scrofa (pig) | |
| 56 | HB (e) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 154 | 17384.7 | 1 | UniProt (A0A8D1EYI7) Pfam (PF10183) | Sus scrofa (pig) | |
| 57 | IB (f) | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 76 | 8664.1 | 1 | UniProt (A0A8D1EYQ2) | Sus scrofa (pig) | |
| 58 | JB (g) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 122 | 14327.7 | 1 | UniProt (A0A480JRW3) Pfam (PF06374) | Sus scrofa (pig) | |
| 59 | KB (h) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 106 | 12506.6 | 1 | UniProt (A0A4X1VX77) Pfam (PF10200) | Sus scrofa (pig) | |
| 60 | LB (j) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 12998.4 | 1 | UniProt (O79880) Pfam (PF00507) | Sus scrofa (pig) | |
| 61 | MB (k) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10827.3 | 1 | UniProt (P56632) Pfam (PF00420) | Sus scrofa (pig) | NADH dehydrogenase subunit 4L |
| 62 | NB (l) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68695.5 | 1 | UniProt (Q9TDR1) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Sus scrofa (pig) | NADH dehydrogenase subunit 5 |
| 63 | OB (n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 58 | 7044.3 | 1 | UniProt (A0A4X1SNY5) Pfam (PF08040) | Sus scrofa (pig) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 64 | PB (o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 129 | 15117.4 | 1 | UniProt (A0A4X1T6M0) Pfam (PF07225) | Sus scrofa (pig) | |
| 65 | QB (r) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35667.5 | 1 | UniProt (O79874) Pfam (PF00146) | Sus scrofa (pig) | NADH dehydrogenase subunit 1 |
| 66 | RB (s) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 249 | 27760.8 | 1 | UniProt (F1SLR1) Pfam (PF06747) | Sus scrofa (pig) | Complex I-19kD,NADH-ubiquinone oxidoreductase 19 kDa subunit |
| 67 | ZB (R) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 110 | 12172.8 | 1 | UniProt (A0A480TFA5) Pfam (PF15880) | Sus scrofa (pig) | Complex I-9kD,NADH-ubiquinone oxidoreductase 9 kDa subunit |
| 68 | CC, DC (Ak) | HEME-A | non-polymer | 852.8 | 2 | Chemie (HEA) | |||
| 69 | EC, FC, LC, OC (2, 4, E, G) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 4 | Chemie (FES) | |||
| 70 | GC, HC, UC, VC (7, w) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 71 | IC, WC (8, x) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) | |||
| 72 | JC (B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 73 | KC, MC, NC, PC, QC... (B, G, H, I) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 74 | SC (L) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 75 | TC (Q) | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate | non-polymer | 568.7 | 1 | Chemie (ZMP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 80 |
| Total formula weight | 1890314.4 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 9992.2 | |
| All* | Total formula weight | 1900306.6 |
