9BU7
Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Protein Rep68 | polymer | 491 | 55896.2 | 7 | UniProt (P03132) Pfam (PF08724) Pfam (PF01057) | adeno-associated virus 2 | |
| 2 | H (H) | DNA (21-MER) | polymer | 21 | 6463.1 | 1 | Homo sapiens | ||
| 3 | I (I) | DNA (21-MER) | polymer | 21 | 6428.2 | 1 | Homo sapiens | ||
| 4 | J, L, N (E, F, G) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 3 | Chemie (AGS) | |||
| 5 | K, M (E, F) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F, G: 2 - 490 (UniProt: P03132)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | - | expression tag |
| Ser 151 | Cys 151 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 404164.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1618.4 | |
| All* | Total formula weight | 405782.9 |
