9BTJ
Rhesus Fab 6561-a.01 in complex with HIV-1 Ce1176.A3 RnS SOSIP Env
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Fab 6561-a.01 light chain | polymer | 217 | 23076.5 | 1 | Macaca mulatta | ||
| 2 | B (H) | Fab 6561-a.01 heavy chain | polymer | 246 | 27288.5 | 1 | Macaca mulatta | ||
| 3 | C, E, G (G, A, D) | Envelope glycoprotein gp120 | polymer | 477 | 53648.9 | 3 | UniProt (C6G0D7) Pfam (PF00516) | Human immunodeficiency virus 1 | Env polyprotein |
| 4 | D, F, H (B, C, E) | Envelope glycoprotein gp41 | polymer | 153 | 17240.5 | 3 | UniProt (C6G0E7) Pfam (PF00517) | Human immunodeficiency virus 1 | Env polyprotein |
| 5 | AA, BA, CA, GA, HA... (a, b, c, g, h...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 20 | In PDB GlyTouCan (G42666HT) | |||
| 6 | DA, J, N, NA, T (d, I, N, n, T) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 5 | In PDB GlyTouCan (G22768VO) | |||
| 7 | K, MA, X (J, m, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 8 | O (O) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
| 9 | P (P) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G80966KZ) | |||
| 10 | U (U) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 1 | In PDB GlyTouCan (G83161QT) | |||
| 11 | EA (e) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 12 | FA (f) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 13 | AB, AC, BB, BC, CB... (G, D, B, A, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 51 | Chemie (NAG) |
Sequence modifications
G, A, D: 33 - 508 (UniProt: C6G0D7)
B, C, E: 512 - 664 (UniProt: C6G0E7)
| PDB | External Database | Details |
|---|---|---|
| Gly 29 | - | expression tag |
| Pro 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Glu 32 | - | expression tag |
| Asn 130 | Thr 129 | conflict |
| Cys 201 | Ile 196 | conflict |
| Thr 202 | Ala 197 | conflict |
| Ile 204 | Ala 199 | conflict |
| Val 286 | Ile 281 | conflict |
| Leu 288 | Phe 283 | conflict |
| Met 302 | Asn 297 | conflict |
| Leu 320 | Thr 313 | conflict |
| Pro 329 | Ala 323 | conflict |
| Ile 333 | Val 327 | conflict |
| Cys 433 | Ala 424 | conflict |
| Asn 448 | Thr 439 | conflict |
| Ser 481 | Asn 472 | conflict |
| Cys 501 | Ala 492 | conflict |
| Arg 509 | - | expression tag |
| Arg 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asn 535 | Ile 526 | conflict |
| Pro 559 | Ile 550 | conflict |
| Gly 569 | Thr 560 | conflict |
| Phe 573 | Ile 564 | conflict |
| Glu 588 | Lys 579 | conflict |
| Val 589 | Asp 580 | conflict |
| Cys 605 | Thr 596 | conflict |
| Thr 613 | Ser 604 | conflict |
| Thr 618 | Ser 609 | conflict |
| Gly 636 | Asp 627 | conflict |
| Phe 651 | Ile 642 | conflict |
| Ile 655 | Lys 646 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 263033.2 | |
| Branched | Number of molecules | 33 |
| Total formula weight | 20815.1 | |
| Non-Polymers* | Number of molecules | 51 |
| Total formula weight | 11281.6 | |
| All* | Total formula weight | 295129.9 |
