9BTI
Rhesus Fab 40591-a.01 in complex with T250.4 RnS SOSIP Env
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, G (B, A, F) | Envelope glycoprotein gp41 | polymer | 153 | 17268.5 | 3 | UniProt (A0A8A0W558) UniProt (by SIFTS) (B0F016) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, F, H (G, C, H) | Envelope glycoprotein gp120 | polymer | 479 | 54113.4 | 3 | UniProt (A0A8A0W558) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | C (D) | Fab 40591-a.01 heavy chain | polymer | 245 | 26200.2 | 1 | Macaca mulatta | ||
| 4 | D (E) | Fab 40591-a.01 light chain | polymer | 214 | 23308.8 | 1 | Macaca mulatta | ||
| 5 | I, R (I, R) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 6 | AA, BA, CA, DA, GA... (a, b, c, d, g...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 18 | In PDB GlyTouCan (G42666HT) | |||
| 7 | EA, N, W (e, N, W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 8 | FA, O, X (f, O, X) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 9 | IA (i) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G02763QD) | |||
| 10 | AB, JA, KA, LA, MA... (H, G, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence modifications
B, A, F: 512 - 664 (UniProt: A0A8A0W558)
G, C, H: 31 - 511 (UniProt: A0A8A0W558)
| PDB | External Database | Details |
|---|---|---|
| Asn 535 | Ile 527 | conflict |
| Pro 559 | Ile 551 | conflict |
| Gly 569 | Thr 561 | conflict |
| Phe 573 | Ile 565 | conflict |
| Glu 588 | Lys 580 | conflict |
| Val 589 | Asp 581 | conflict |
| Cys 605 | Thr 597 | conflict |
| Thr 613 | Ser 605 | conflict |
| Gly 636 | Ser 628 | conflict |
| Glu 648 | Gln 640 | conflict |
| Phe 651 | Asn 643 | conflict |
| Ile 655 | Lys 647 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 29 | - | expression tag |
| Pro 30 | - | expression tag |
| Asn 33 | Lys 31 | conflict |
| Asn 80 | Arg 78 | conflict |
| Ile 84 | Met 82 | conflict |
| Asn 99 | Ser 97 | conflict |
| Leu 175 | Phe 168 | conflict |
| Leu 179 | Thr 172 | conflict |
| Val 182 | Glu 175 | conflict |
| Cys 201 | Ile 194 | conflict |
| Ile 204 | Ala 197 | conflict |
| Thr 236 | Lys 229 | conflict |
| Ser 274 | Val 267 | conflict |
| Ile 277 | Thr 270 | conflict |
| Thr 278 | Ile 271 | conflict |
| Met 302 | Asn 295 | conflict |
| Leu 320 | Thr 311 | conflict |
| Pro 329 | Ala 321 | conflict |
| Arg 350 | Ser 342 | conflict |
| Thr 358 | Lys 349 | conflict |
| Ser 364 | His 355 | conflict |
| Thr 372 | Ile 363 | conflict |
| Asn 377 | Val 368 | conflict |
| Arg 419 | Glu 412 | conflict |
| Ile 423 | Phe 416 | conflict |
| Cys 433 | Ala 426 | conflict |
| Asn 448 | Asp 441 | conflict |
| Gly 460 | Pro 452 | conflict |
| Cys 501 | Ala 493 | conflict |
| Arg 509 | Glu 501 | conflict |
| Arg 510 | Lys 502 | conflict |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 263654.6 | |
| Branched | Number of molecules | 27 |
| Total formula weight | 14701.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 282337.9 |
