9BT6

Crystal structure of Chorismate Mutase from Mycobacterium tuberculosis in complex with the cyclic peptide inhibitor L2.1 (monoclinic P form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Secreted chorismate mutase	polymer	205	22973.4	8	UniProt (P9WIB9) Pfam (PF01817)	Mycobacterium tuberculosis	CM,*MtCM
2	I, J, K, L, M... (a, b, c, d, e...)	Peptide L2.1	polymer	14	1766.1	8		Mycobacterium tuberculosis
3	AA, BA, CA, DA, EA... (C, D, E, F, G...)	SULFATE ION	non-polymer		96.1	28	Chemie (SO4)
4	SA, TA, UA, VA, WA... (A, B, D, E, G...)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 34 - 199 (UniProt: P9WIB9)

PDB	External Database	Details
Gly 200	-	expression tag
Leu 201	-	expression tag
Asn 202	-	expression tag
Asp 203	-	expression tag
Ile 204	-	expression tag
Phe 205	-	expression tag
Glu 206	-	expression tag
Ala 207	-	expression tag
Gln 208	-	expression tag
Lys 209	-	expression tag
Ile 210	-	expression tag
Glu 211	-	expression tag
Trp 212	-	expression tag
His 213	-	expression tag
Glu 214	-	expression tag
Ser 215	-	expression tag
Ser 216	-	expression tag
Gly 217	-	expression tag
Leu 218	-	expression tag
Val 219	-	expression tag
Pro 220	-	expression tag
Arg 221	-	expression tag
Gly 222	-	expression tag
Ser 223	-	expression tag
Ala 224	-	expression tag
Ala 225	-	expression tag
Gly 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag
His 233	-	expression tag
His 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
Glu 237	-	expression tag
Leu 238	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	197915.7
Non-Polymers*	Number of molecules	28
	Total formula weight	2689.8
All*	Total formula weight	200605.5

*Water molecules are not included.