9BRW
SARS-CoV-2 Papain-like Protease (PLpro) with Fragment 7
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Papain-like protease nsp3 | polymer | 323 | 36681.6 | 4 | UniProt (P0DTC1) Pfam (PF08715) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO |
2 | A, B, C, D | N-(2-chlorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 259.7 | 4 | Chemie (A1ARL) | |||
3 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
4 | B, C | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
5 | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 0 - 316 (UniProt: P0DTC1)
PDB | External Database | Details |
---|---|---|
Met -1 | - | initiating methionine |
Ser 111 | Cys 1674 | engineered mutation |
Ser 270 | Cys 1833 | engineered mutation |
Leu 317 | - | expression tag |
Glu 318 | - | expression tag |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 146726.3 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1513.1 | |
All* | Total formula weight | 148239.5 |