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9BR2

Inward-facing, ATP-bound Multidrug Resistance-associated Protein 2 (MRP2) (E1462Q)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-binding cassette sub-family C member 2polymer1545174391.41UniProt (Q92887)
Pfam (PF00664)
Pfam (PF00005)
Homo sapiens (human)Canalicular multidrug resistance protein,Canalicular multispecific organic anion transporter 1,Multidrug resistance-associated protein 2
2B, C
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
3D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4E, F, G, H, N...
(A)
UNKNOWN LIGANDnon-polymer790.18Chemie (UNL)
5I, J, K, L, M
(A)
CHOLESTEROLnon-polymer386.75Chemie (CLR)
Sequence modifications
A: 1 - 1545 (UniProt: Q92887)
PDBExternal DatabaseDetails
Gln 1462Glu 1462engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight174391.4
Non-Polymers*Number of molecules16
Total formula weight9293.1
All*Total formula weight183684.5
*Water molecules are not included.

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PDB entries from 2025-07-30

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