9BQA
Human Topoisomerase 2 Beta ATPase domain bound to BNS22 and non-hydrolyzable ATP analog AMPPNP
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA topoisomerase 2-beta | polymer | 397 | 45262.1 | 1 | UniProt (Q02880) Pfam (PF02518) Pfam (PF00204) | Homo sapiens (human) | DNA topoisomerase II,beta isozyme |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | 8-(3,4-dihydroquinoline-1(2H)-carbonyl)-5,7-dimethoxy-4-propyl-2H-1-benzopyran-2-one | non-polymer | 407.5 | 1 | Chemie (A1ASD) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 45 - 438 (UniProt: Q02880)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Asn 43 | - | expression tag |
| Ala 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45262.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1030.1 | |
| All* | Total formula weight | 46292.1 |
