9BQ6
Human Topoisomerase 2 Alpha ATPase domain bound to non-hydrolyzable ATP analog AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA topoisomerase 2-alpha | polymer | 399 | 45484.2 | 2 | UniProt (P11388) Pfam (PF02518) Pfam (PF00204) | Homo sapiens (human) | DNA topoisomerase II,alpha isozyme |
| 2 | C, E (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 424 (UniProt: P11388)
| PDB | External Database | Details |
|---|---|---|
| Ser 26 | - | expression tag |
| Asn 27 | - | expression tag |
| Ala 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90968.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1061.0 | |
| All* | Total formula weight | 92029.4 |
