9BPN

Crystal structure of the allosteric MKP5 mutant Y435W

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dual specificity protein phosphatase 10	polymer	148	17089.6	2	UniProt (Q9Y6W6) Pfam (PF00782)	Homo sapiens (human)	Mitogen-activated protein kinase phosphatase 5,MAP kinase phosphatase 5,MKP-5
2	C, D (A, B)	water	water		18.0	35	Chemie (HOH)

Sequence modifications

A, B: 320 - 466 (UniProt: Q9Y6W6)

PDB	External Database	Details
Met 319	-	initiating methionine
Trp 435	Tyr 435	engineered mutation

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.