9BPH
CRYO-EM STRUCTURE OF CARDIAC MUSCLE ALPHA-ACTIN M305L HCM MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Actin, alpha cardiac muscle 1 | polymer | 375 | 41825.5 | 4 | UniProt (P68032) Pfam (PF00022) | Homo sapiens (human) | Alpha-cardiac actin |
| 2 | E, G, I, K (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, H, J, L (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) |
Sequence modifications
A, B, C, D: 1 - 375 (UniProt: P68032)
| PDB | External Database | Details |
|---|---|---|
| Leu 305 | Met 307 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 167302.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1806.0 | |
| All* | Total formula weight | 169108.1 |
