9BOZ
Cryo-EM structure of human Glycine Receptor alpha3-beta heteromer in presence of glycine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glycine receptor subunit alpha-3 | polymer | 422 | 48936.5 | 4 | UniProt (O75311) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 2 | E (E) | Glycine receptor subunit beta,Green fluorescent protein | polymer | 680 | 76584.5 | 1 | UniProt (P48167) UniProt (A0A9X4KGN5) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | Glycine receptor 58 kDa subunit |
| 3 | F, G, H, I, J (A, B, C, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 1 - 431 (UniProt: O75311)
E: 3 - 333 (UniProt: P48167)
E: 333 - 342 (UniProt: A0A9X4KGN5)
E: 342 - 475 (UniProt: P48167)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 362 | deletion |
| - | Leu 363 | deletion |
| - | Glu 364 | deletion |
| - | Lys 365 | deletion |
| - | Phe 366 | deletion |
| - | Tyr 367 | deletion |
| - | Arg 368 | deletion |
| - | Phe 369 | deletion |
| - | Ser 370 | deletion |
E: 333 - 342 (UniProt: A0A9X4KGN5)
| PDB | External Database | Details |
|---|---|---|
| Phe 335 | Leu 72 | conflict |
| Ser 335 | Thr 73 | conflict |
| His 342 | Leu 239 | conflict |
| Ser 342 | - | linker |
| Gly 342 | - | linker |
| Ser 342 | - | linker |
| Gly 342 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 333 | - | linker |
| Gly 333 | - | linker |
| Ser 333 | - | linker |
| Ser 333 | - | linker |
| Ala 333 | - | linker |
| Ala 333 | - | linker |
| Ala 333 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 272330.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 273436.7 |
